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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L5
All Species:
19.7
Human Site:
S582
Identified Species:
33.33
UniProt:
Q9HCM4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCM4
NP_065960.2
733
81856
S582
H
K
V
T
K
E
D
S
L
L
S
H
K
N
A
Chimpanzee
Pan troglodytes
XP_001157953
733
81845
S582
H
K
V
T
K
E
D
S
L
L
S
H
K
N
A
Rhesus Macaque
Macaca mulatta
XP_001088764
726
81122
S576
H
K
V
T
K
E
D
S
L
L
S
H
K
N
A
Dog
Lupus familis
XP_532028
914
101864
F670
V
G
K
E
E
S
T
F
V
N
I
N
K
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGS1
731
81617
S581
H
K
V
T
R
E
D
S
L
L
T
H
K
N
A
Rat
Rattus norvegicus
Q5FVG2
731
81700
S581
H
K
A
T
R
E
D
S
L
L
T
H
K
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
A582
G
Q
A
A
L
T
A
A
F
S
A
V
P
R
H
Chicken
Gallus gallus
XP_422083
502
57358
Q354
Y
S
G
K
T
E
Y
Q
T
T
K
T
N
K
A
Frog
Xenopus laevis
NP_001080234
498
57093
K350
S
R
F
R
Y
S
G
K
T
E
Y
Q
T
T
K
Zebra Danio
Brachydanio rerio
O57457
619
70690
R471
H
R
R
R
S
R
S
R
G
N
T
S
S
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
T759
S
S
S
S
T
S
S
T
A
T
T
T
T
N
G
Honey Bee
Apis mellifera
XP_623974
809
90976
I661
S
L
D
S
W
G
Q
I
E
Q
K
T
T
Q
L
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
Y783
A
N
L
A
K
N
R
Y
R
D
V
C
P
Y
D
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
A584
S
T
Q
T
E
K
V
A
D
N
K
Y
K
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.2
39.8
N.A.
83.9
83.6
N.A.
56.5
56.6
54.4
28.5
N.A.
36.8
38.9
24.3
39.1
Protein Similarity:
100
99.3
96.3
52.1
N.A.
89.2
88.4
N.A.
65.1
62.2
60.9
44.7
N.A.
51.8
53.1
40.1
56.7
P-Site Identity:
100
100
100
6.6
N.A.
86.6
80
N.A.
0
13.3
0
6.6
N.A.
6.6
0
6.6
13.3
P-Site Similarity:
100
100
100
33.3
N.A.
100
93.3
N.A.
20
20
6.6
26.6
N.A.
26.6
6.6
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
15
0
0
8
15
8
0
8
0
0
0
43
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
8
0
0
0
36
0
8
8
0
0
0
0
8
% D
% Glu:
0
0
0
8
15
43
0
0
8
8
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
8
8
0
0
0
0
0
0
% F
% Gly:
8
8
8
0
0
8
8
0
8
0
0
0
0
8
8
% G
% His:
43
0
0
0
0
0
0
0
0
0
0
36
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% I
% Lys:
0
36
8
8
29
8
0
8
0
0
22
0
50
15
8
% K
% Leu:
0
8
8
0
8
0
0
0
36
36
0
0
0
8
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
0
0
22
0
8
8
43
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% P
% Gln:
0
8
8
0
0
0
8
8
0
8
0
8
0
8
0
% Q
% Arg:
0
15
8
15
15
8
8
8
8
0
0
0
0
8
0
% R
% Ser:
29
15
8
15
8
22
15
36
0
8
22
8
8
0
15
% S
% Thr:
0
8
0
43
15
8
8
8
15
15
29
22
22
8
0
% T
% Val:
8
0
29
0
0
0
8
0
8
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
0
8
8
0
0
8
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _